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Innes is da Man!
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i would cut back on the 50% changes, maybe do 25% at a time, too much of a water change so often can be dramatic for the filtraion, also when you do your changes, turn off the filters so the new water ( which should be treated with de-chlorinizer) will not harm the bacteria in the filter, as for the pop eye, the marycin should work or there are other products that will help as well
 
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